Research

Voice as a Digital Biomarker

Digital Biomarker

Health Screening

Machine Learning

Voice-based Disease Detection

The human voice contains rich physiological and neurological information that can serve as a powerful, non-invasive digital biomarker for disease detection. Our research focuses on developing advanced artificial intelligence methods to analyze vocal signals for scalable, low-cost, and accessible medical screening.

A key challenge in voice-based diagnostics is ensuring that AI models remain reliable across different recording environments, devices, languages, and patient populations. We address this through domain generalization strategies that enable models to maintain performance even when applied to new and unseen conditions. By improving robustness and transferability, we aim to bridge the gap between laboratory research and real-world clinical deployment.

In parallel, we investigate the discovery of novel voice biomarkers — subtle acoustic and phonatory patterns that reflect underlying physiological or neurological changes. By combining signal processing, machine learning, and clinical insight, our work advances voice as a practical tool for early detection, risk assessment, and remote health monitoring.

Our long-term vision is to establish voice-based AI systems as reliable, clinically meaningful digital health technologies that enhance accessibility and support data-driven medical decision-making.

Related publications:

2025

M. Hireš, P. Drotár

Augmented speech generalization in parkinson's disease detection

Journal: 2025 IEEE 38th International Symposium on Computer-Based Medical Systems.

J. Gazda, P. Drotár, M. Hireš, S. Dražilová, M. Janičko, P. Jarčuška

Diagnostic potential of speech artificial intelligence analysis in minimal hepatic encephalopathy

Journal: Journal of Hepatology.

2023

Q. C. Ngo, M. A. Motin, N. D. Pah, P. Drotár, P. Kempster, D. Kumar

Computerized analysis of speech and voice for parkinson's disease: a systematic review

Journal: Computer Methods and Programs in Biomedicine

M. Hireš, P. Drotár, N. D. Pah, Q. C. Ngo, D. K. Kumar

On the inter-dataset generalization of machine learning approaches to Parkinson's disease detection from voice

Journal: International Journal of Medical Informatics

2022

M. Hireš, M. Gazda, P. Drotár, N. D. Pah, M. A. Motin, D. K. Kumar

Convolutional neural network ensemble for parkinson's disease detection from voice recordings

Journal: Computers in Biology and Medicine

2021

L. Vavrek, M. Hireš, D. Kumar, P. Drotár

Deep convolutional neural network for detection of pathological speech

Journal: SAMI 2021